Clinical and Neuropathological Study of Six Patients with Spastic Paraparesis Associated with HTLV-I
نویسندگان
چکیده
منابع مشابه
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients.
OBJECTIVE Tropical Spastic Paraparesis/HTLV-I Associated Myelopathy (TSP/HAM) is a chronic myelopathy, and pain has been mentioned as a frequent sensory symptom in this condition. The authors aimed at analyzing this symptom in a TSP/HAM patients series. METHOD For this, 46 patients were analyzed considering demographic and clinical characteristics and complaint of pain as to verbal descriptio...
متن کاملDisulfide-Mediated Apoptosis of HTLV-I-Infected Cells in Patients with HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis
Background: This study was conducted to construct a basis for the therapeutic strategy against human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) using a compound containing the disulfide moiety prosultiamine, which is a homologue of allithiamine originally synthesized by allicin and thiamine-thiol, for the targeting of HTLV-I-infected cells....
متن کاملQuality of life in patients with HTLV-I associated myelopathy/tropical spastic paraparesis.
OBJECTIVE To assess the quality of life (QoL) of patients with HTLV-I-associate myelopathy/tropical spastic paraparesis (HAM/TSP) and to correlate it with specific aspects of the disease. METHODS Fifty-seven HAM/TSP patients completed the SF-36 QoL questionnaire. They were also asked about common complaints related to the disease, and we looked for associations between QoL and these complaint...
متن کاملThe Impact of Immune Response on HTLV-I in HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)
Human T lymphotropic virus type I (HTLV-I) is a retrovirus which is associated with adult T cells leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a minority of HTLV-I-infected individuals. It is not clear why a minority of HTLV-I-infected individuals develop HAM/TSP and majority remains lifelong carriers. It seems that the interaction between the v...
متن کامل[HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)].
Human T lymphotropic virus type I(HTLV-I) is associated with the nonfatal neurologic disease, HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Many clinical signs of involvement outside the central nervous system (CNS) have been described in some patients with HAM/TSP and have triggered the discovery of some HTLV-I-associated concepts in the infected individuals without sign...
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ژورنال
عنوان ژورنال: Journal of Neuropathology and Experimental Neurology
سال: 1997
ISSN: 0022-3069
DOI: 10.1097/00005072-199704000-00009